Catch up on our latest clinical research and news

Our rigorous clinical research shows the Mirvie RNA platform can predict preeclampsia and preterm birth months in advance.1,2,3

Publications and Press Releases

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Mirvie Raises $60 Million Funding Round to Shape the Future of Pregnancy Health
May 17, 2022
Mirvie, a pioneer in predicting unexpected pregnancy complications, today announced it has raised a total of $90 million to date following the close of its Series B funding. The financing was led by Decheng Capital with additional funding from funds and accounts managed by BlackRock, Foresite Capital, General Catalyst, GV, Khosla Ventures, and Mayfield as well as a debt facility with Comerica Bank. The funding will support Mirvie’s continued clinical and commercial development of the proprietary Mirvie RNA platform, which is the first to predict preeclampsia and preterm birth months before they happen by revealing the underlying biology of each pregnancy.
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Mirvie Receives FDA Breakthrough Device Designation for First Test Designed to Indicate Risk of Preeclampsia Months Before Symptoms Occur
May 3, 2022
Mirvie, a pioneer in predicting unexpected pregnancy complications, today announced the company received U.S. Food and Drug Administration (FDA) Breakthrough Device designation for its test to indicate a woman’s individualized risk of developing preeclampsia before symptoms occur. The test is powered by the proprietary Mirvie RNA platform, which is designed to predict the risk of unexpected complications by revealing the underlying biology of each pregnancy.
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Study Published in The American Journal of Obstetrics and Gynecology Shows The Mirvie RNA Platform is First to Predict Preterm Birth by Revealing the Underlying Biology of Each Pregnancy
April 13, 2022
Mirvie, a pioneer in predicting unexpected pregnancy complications, today announced the publication of a study in the American Journal of Obstetrics and Gynecology, a leading obstetrics and gynecology medical journal. The results demonstrate the Mirvie RNA platform is first to predict preterm birth by revealing the underlying biology of each pregnancy. The breakthrough research shows the platform can predict the condition months before symptoms occur and identify distinct biological pathways driving its development.
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Late-breaking Data Presented at SMFM 2022 Annual Meeting Shows The Mirvie RNA Platform is First to Reveal The Underlying Biology of Preterm Birth
FEBRUARY 4, 2022
Mirvie, a pioneer in predicting unexpected pregnancy complications, today announced data presented at the Society for Maternal-Fetal Medicine 42nd Annual Pregnancy Meeting (SMFM 2022) demonstrates the Mirvie RNA platform is first to predict preterm birth by revealing the underlying biology of each pregnancy. The breakthrough research shows the platform can predict the condition months before symptoms occur and identify distinct biological pathways driving its development.
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Study Published in Nature Shows Mirvie Can Predict Pregnancy Complications Months Before They Happen Using New, Proprietary RNA Platform
JANUARY 5, 2022
Mirvie, a pioneer in predicting unexpected pregnancy complications, today announced the publication of a study in Nature proving the proprietary Mirvie RNA platform is first to predict unexpected complications by revealing the underlying biology of each pregnancy. The research analyzed the largest and most diverse dataset of maternal transcriptomes to date. The platform opens a new window into pregnancy health for women to act and their doctors to intervene before unexpected complications become a crisis.
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Mirvie is redefining pregnancy health by developing the first early detection RNA test to address pregnancy complications which impact 45 million women globally
APRIL 27, 2021
Pregnancy complications affect 45 million women globally each year, five times the rate of cancer incidence. Today there is no reliable way to identify those pregnancies at-risk. The goal of Mirvie’s simple blood test is the early detection of complications such as preterm birth, preeclampsia and gestational diabetes, which has the potential to reduce pregnancy healthcare costs by up to 65%.
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Media Coverage

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Michal Elovitz, MD, discusses new preterm birth data at SMFM
“We see very unique RNA profiles that are associated with the development of preterm birth months ahead of time. If we’re actually able to say, I not only can identify who is at risk, I can identify the biology that makes you at risk, it just opens up this whole new world for pregnancy health and for moms.”
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Inside Precision Medicine – Bridging a Gap in Pregnancy Health
After being neglected for many years, adverse pregnancy outcomes such as pre-eclampsia and preterm birth are now the focus of a small group of researchers and companies that are aiming to fill a much-needed gap in the clinical testing market.
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Predicting preeclampsia from a blood test holds promise for pregnancy complications
Preeclampsia is a potentially serious problem that usually surfaces late in pregnancy, posing an immediate risk of preterm birth, stillbirth, and death as well a later danger of stroke for the mother. New research published Wednesday in Nature shows how RNA molecules sequenced from a single blood sample could predict preeclampsia months before symptoms appear, holding promise for detecting and treating this and other pregnancy complications before they cause harm.
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Mirvie touts new data on preterm birth prediction for its personalized pregnancy health test
“Early detection of preterm birth and identification of distinct pathways driving it is a fantastic advance. This new knowledge has real potential to improve the application of existing interventions and aid the development of new therapies for preterm birth that directly target its cause.”
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A blood test to predict complications of pregnancy
Cell-free RNA transcripts in maternal blood can be analysed to monitor the progression of pregnancy and to predict a potentially harmful pregnancy-specific condition called pre‑eclampsia.
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Mirvie RNA test aims to predict pregnancy complications
Maneesh Jain, CEO and co-founder of Mirvie, a proprietary RNA platform that uses blood samples to predict pregnancy complications such as preeclampsia, sits down with Contemporary OB/GYN to discuss the potential of the test.
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Blood test may one day predict severe pregnancy complication
“It’s often in the first trimester that a lot of the onset of the condition happens biologically,” although symptoms show up late in pregnancy, said Maneesh Jain, Mirvie’s CEO. Detecting preeclampsia after symptoms arise “leaves you very little time to address the challenge. And it’s mostly crisis management.”
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Blood testing identifies preeclampsia, disease risks in pregnancy months before symptoms
Researchers predicted preeclampsia in 75% of cases and preterm birth at nearly the same rate by analyzing maternal, fetal and placental RNA circulating in the mother’s blood during pregnancy, according to a study published in Nature.
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Simple blood test is first to identify pregnant women at risk of pre-eclampsia even before any symptoms develop
The new research was conducted by a global collaborative involving experts at King’s College London, Guy’s and St Thomas’ NHS Foundation Trust, Brigham and Women’s Hospital in Boston, Massachusetts and US biotechnology firm Mirvie.
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Maternal Cell-Free RNA Can Gauge Preeclampsia Risk Months Before Symptoms, Study Finds
By comparing the cell-free RNA profiles of pregnant women with and without preeclampsia, the Mirvie-led team developed a model to predict who might develop the condition. The researchers found the model could identify three-quarters of women who would later develop preeclampsia early in their pregnancies.
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New Blood Test Could Detect Whether Pregnant Women Will Be Affected by Preeclampsia
A new blood test could detect whether pregnant women will be affected by preeclampsia, which can cause stroke, organ damage and preterm birth, months before its symptoms appear.
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Simple test could predict dangerous blood pressure in pregnant women
The test would also be important because it does not depend on race (including race did not improve the predictions), but instead on what is actually happening at a biological level in that individual, the authors say.
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Cell-Free RNA Testing For Pregnancy Complications
Mirvie is developing a revolutionary, cell-free RNA test using a simple blood sample to assess the risk of developing severe pregnancy complications.
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Improving Pregnancy Health: How We Can Predict Challenges Sooner
Obstetrics has improved in treating conditions like preterm birth and preeclampsia, but the ability to predict who’s at risk is “ripe for exploration and innovation.”
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Meet Mirvie, a Femtech Startup Creating a Blood Test for Early Detection of Pregnancy Complications
Earlier today Mirvie announced it is making rapid progress toward developing a simple, personalized blood test with the potential for early detection of pregnancy complications, such as preterm birth, preeclampsia and gestational diabetes, which affect 1 in 5 women. Currently, there is no reliable way to identify if a mother is at risk for these significant pregnancy complications.…
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A former Grail exec and the president of the Chan Zuckerberg Biohub are developing a blood test to help expectant mothers understand the chances of pregnancy complications
With Mirvie, Quake and Jain are attempting to apply liquid biopsy technology more commonly found in oncology centers to pregnancy, a more common but significantly less funded area of research, according to Jain.
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Noninvasive blood tests for fetal development predict gestational age and preterm delivery
Low-cost methods for monitoring fetal development could improve prenatal care, especially in low-resource settings. By measuring the levels of certain placental RNA transcripts in maternal blood…
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10 Breakthrough Technologies 2019 – How we’ll invent the future.
We asked Gates to choose this year’s list of inventions that will change the world for the better. I was honored when MIT Technology Review invited me to be the first guest curator of its 10 Breakthrough Technologies…
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Complications from preterm birth are the leading cause of death worldwide in children under five.
Fifteen million babies are born pre­maturely each year. Stephen Quake’s daughter, Zoe, was one of them: she arrived via emergency C-section after Quake and his wife, Athina, made a middle-of-the-night dash to the emergency room, a month before Zoe was due. She spent her first night in an incubator, and her father, a bioengineer then at Caltech, wondered why birth couldn’t be more predictable…
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