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Inside Precision Medicine – Bridging a gap in pregnancy health

February 11, 2022

After being neglected for many years, adverse pregnancy outcomes such as pre-eclampsia and preterm birth are now the focus of a small group of researchers and companies that are aiming to fill a much-needed gap in the clinical testing market.

Mirvie touts new data on preterm birth prediction for its personalized pregnancy health test

February 4, 2022

“Early detection of preterm birth and identification of distinct pathways driving it is a fantastic advance. This new knowledge has real potential to improve the application of existing interventions and aid the development of new therapies for preterm birth that directly target its cause.”

A blood test to predict complications of pregnancy

January 5, 2022

Cell-free RNA transcripts in maternal blood can be analysed to monitor the progression of pregnancy and to predict a potentially harmful pregnancy-specific condition called pre‑eclampsia.

Mirvie RNA test aims to predict pregnancy complications

January 12, 2022

Maneesh Jain, CEO and co-founder of Mirvie, a proprietary RNA platform that uses blood samples to predict pregnancy complications such as preeclampsia, sits down with Contemporary OB/GYN to discuss the potential of the test.

Blood test may one day predict severe pregnancy complication

January 5, 2022

“It’s often in the first trimester that a lot of the onset of the condition happens biologically,” although symptoms show up late in pregnancy, said Maneesh Jain, Mirvie’s CEO. Detecting preeclampsia after symptoms arise “leaves you very little time to address the challenge. And it’s mostly crisis management.”

Blood testing identifies preeclampsia, disease risks in pregnancy months before symptoms

January 7, 2022

Researchers predicted preeclampsia in 75% of cases and preterm birth at nearly the same rate by analyzing maternal, fetal and placental RNA circulating in the mother’s blood during pregnancy, according to a study published in Nature.

Simple blood test is first to identify pregnant women at risk of pre-eclampsia even before any symptoms develop

January 5, 2022

The new research was conducted by a global collaborative involving experts at King’s College London, Guy’s and St Thomas’ NHS Foundation Trust, Brigham and Women’s Hospital in Boston, Massachusetts and US biotechnology firm Mirvie.

Maternal cell-free RNA can gauge preeclampsia risk months before symptoms, study finds

January 5, 2022

By comparing the cell-free RNA profiles of pregnant women with and without preeclampsia, the Mirvie-led team developed a model to predict who might develop the condition. The researchers found the model could identify three-quarters of women who would later develop preeclampsia early in their pregnancies.

New blood test could detect whether pregnant women will be affected by preeclampsia

January 5, 2022

A new blood test could detect whether pregnant women will be affected by preeclampsia, which can cause stroke, organ damage and preterm birth, months before its symptoms appear.

Simple test could predict dangerous blood pressure in pregnant women

January 5, 2022

The test would also be important because it does not depend on race (including race did not improve the predictions), but instead on what is actually happening at a biological level in that individual, the authors say.

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